Chronic kidney disease is a progressive disorder that has been influenced with many factors. Most of the patients has altered Ca P metabolism and these dis orders are the contributing factors of the disease progression. It has been recently documented that FGF23 and Klotho are the key factors of PTH secretion Ca-P metabolism. This study aimed to evaluate the impact of Klotho and FGF23 on the progression of stage 3-4 chronic kidney disease.
Study Type
OBSERVATIONAL
Enrollment
90
Ankara Education and Research Hospital
Ankara, Turkey (Türkiye)
Progression of kidney disease
Doubling of creatinin, requirement of renal replacement therapy
Time frame: continuous measurement of kidney functions 3 monthly for two years or until the outcome reached
Evaluation of Ca P metabolism
Determination of Ca-P metabolism disorders.
Time frame: 3 monthly for two years or until the outcome reached
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