The purpose of this study is to determine whether rinsing with an amine fluoride/stannous flouride mouthrinse in addition to daily tooth brushing is more effective than tooth brushing alone.
Gingivitis prevalence is 100% among the population. This is mostly due to an inadequate mechanical cleaning of the teeth. However, remaining dental biofilm can be approached by antibacterial mouthrinses. As a consequence of regular use of these mouthrinses, gingivitis can be reduced. Amine fluoride/stannous flouride mouthrinse (ASF)has proved its efficacy in several studies. In the previous years, a new formulation that does not contain ethanol anymore was introduced in the market. Therefore, it is the aim of the study to proof whether rinsing with ASF adjunctive to mechanical oral hygiene is more effective on gingivitis reduction than mechanical oral hygiene alone. In addition, effects on dental plaque, discoloration of teeth and bacterial colonization should be studied.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
SINGLE
Enrollment
180
10 ml qd, oral, topical, 6 months duration
Dreden University of Technology, Universitätsklinikum, Poliklinik für Parodontologie
Dresden, Saxony, Germany
Reduction in gingivitis
To proof whether rinsing with ASF adjunctive to mechanical oral hygiene is more effective on gingivitis reduction than mechanical oral hygiene alone.
Time frame: 6 months
Reduction in plaque
To proof whether rinsing with ASF adjunctive to mechanical oral hygiene is more effective on plaque reduction than mechanical oral hygiene alone.
Time frame: 6 months
Discoloration of teeth
To proof the effect of rinsing with ASF on discoloration of teeth
Time frame: 6 months
Bacterial colonization
To proof whether rinsing with ASF adjunctive to mechanical oral hygiene influences bacterial colonization
Time frame: 6 months
Adverse events
Recording all adverse events over the entire rinsing period
Time frame: 6 months
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