Study Of The Long Term Outcome Of Tuberculous Meningitis In Vietnamese Adults Treated With Adjunctive Dexamethasone

Oxford University Clinical Research Unit, Vietnam340 enrolled

Overview

All patients who were alive at the end of the dexamethasone treatment trial conducted by Oxford University CLinical Research Unit from 2001-2005 (n=340) will be eligible to participate in this long-term follow-up study. All eligible and consenting patients will undergo an assesment consisting of a simple questionnaire, a clinical examination and a blood test. Data collected will focus on survival, neurological disability and tuberculosis relapse. Data will be collected in individual case record forms and entered into a computer database.

Study Type

OBSERVATIONAL

Enrollment

340

Conditions

Tuberculosis Meningitis

Interventions

ObservationOTHER

Collection of mortality data at 5 years post trial

Eligibility

Sex: ALLMin age: 1 YearMax age: 90 Years

Medical Language ↔ Plain English

Inclusion Criteria:Patients were alive at the end of the dexamethasone study (n=340) will be eligible to participate in this long-term follow-up study Informed consent Exclusion Criteria: Patients without informed consent

Outcomes

Primary Outcomes

Survival

Time frame: 5 years

Secondary Outcomes

Neurological disability

Time frame: 5 years

Tuberculosis relapse rate

Time frame: 5 years