Acute fluid collections is common in patients with severe acute pancreatitis (SAP). But the treatment for this is controversial. In this study, the investigators aim to evaluate the different effects of three different treatment protocols which is repeated aspiration, continuous catheter drainage and conservative treatment. The investigators suppose repeated aspiration could not only solve acute fluid collections, but also lower the rate of pancreatic infection.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Enrollment
87
Including antibiotics,somatostatin, proton pump inhibitors and sufficient fluid resuscitation
Department of SICU, Research Institute of General Surgery Jinling Hospital,
Nanjing, Jiangsu, China
RECRUITINGpancreatic infection
Time frame: 28 days
mortality
Time frame: 28 days
inflammation parameters
Time frame: 28 days
intra abdominal pressure
Time frame: 28 days
complications
intestinal fistula , major bleeding, etc.
Time frame: 28 days
ICU duration
Time frame: day one until discharge
hospital duration
Time frame: day one until discharge
SIRS
Time frame: 28 days
MODS
Time frame: 28 days
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