This study is to look at a new vaccine that might prevent meningococcal disease, and to look at the safety of the new vaccine as well as how it is tolerated when given together with Repevax. The study will be done in healthy adolescents.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
PREVENTION
Masking
SINGLE
Enrollment
753
Percentage of Participants Achieving Prespecified Criteria for the Concomitant Antigen
Time frame: 1 month after Vaccination 1
Percentage of Participants With at Least One Adverse Event (AE)
Time frame: Vaccination 1 up to 1 month after Vaccination 3
Geometric Mean Concentration (GMC) for Diphtheria and Tetanus Antigens
Time frame: 1 month after Vaccination 1
GMC for Acellular Pertussis Antigens
Enzyme-linked immunosorbent assay (ELISA) units per milliliter (EU/mL)
Time frame: 1 month after Vaccination 1
Geometric Mean Titer (GMT) for Poliomyelitis Antigens
Time frame: 1 month after Vaccination 1
Percentage of Participants Achieving Serum Bactericidal Assay Using Human Complement (hSBA) Titer Level Greater Than or Equal to (>=) Prespecified Titer Level
Time frame: 1 month after Vaccination 3
This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.
0.5 mL dose, given at 0 months.
Espoo Vaccine Research Clinic
Espoo, Finland
Helsinki South Vaccine Research Clinic
Helsinki, Finland
Ita-Helsinki Vaccine Research Clinic
Helsinki, Finland
Järvenpää Vaccine Research Clinic
Jarvenpaa, Finland
Kokkola Vaccine Research Clinic
Kokkola, Finland
Lahti Vaccine Research Clinic
Lahti, Finland
Oulu Vaccine Research Clinic
Oulu, Finland
Pori Vaccine Research Clinic
Pori, Finland
Seinäjoki Vaccine Research Clinic
Seinäjoki, Finland
Tampereen Yliopisto University Of Tampere
Tampere, Finland
...and 26 more locations