Trial of Individual Psychosocial Interventions for Cancer Patients

Inclusion Criteria: * 21 years of age and older * Able to communicate and understand English well enough to complete assessments and intervention\*\* * Patients solid tumors with advanced disease receiving ambulatory care at MSKCC\*. * Distress Thermometer rating of 4 or greater\* * Patients who do not meet these eligibility criteria may be offered participation as a training case (See inclusion criteria for Training Cases below). Subject Inclusion Criteria- Training Cases * 21 years of age and older * Able to communicate and understand English well enough to complete the intervention\*\* * Patients with solid tumors with advanced disease receiving ambulatory care at MSKCC with a Distress Thermometer rating of 3 or less. or Patients with solid tumors who do not meet eligibility criteria for advanced disease receiving ambulatory care at MSKCC. or Patients solid tumors with advanced disease receiving ambulatory care at MSKCC who have participated in a prior meaning focused intervention study. or Patients with solid tumors with advanced disease receiving ambulatory care at MSKCC who have enrolled in this study, been assigned to the EUC arm, and completed all study requirements including follow-up assessments. \*\*The study treatment manual materials and assessments were designed and validated in English and are not currently available in other languages. Translation of the intervention and questionnaires into other languages would require reestablishing the reliability and validity of them. Therefore, participants must be able to communicate in English. Exclusion Criteria: * In the judgment of the treating physician and/or the consenting professional, presence of significant cognitive impairment (i.e., delirium or dementia) sufficient to preclude meaningful informed consent and/or data collection. * Baseline Karnofsky Performance Rating Scale (KPRS) score below 60 or physical limitations sufficient to preclude participation in a 7 session outpatient psychotherapy intervention. * In the judgment of the consenting professional, severe psychiatric disturbance sufficient that would preclude participation in the intervention (patients whose psychiatric disorder is well controlled on medication will be eligible).