CA125 Levels and Other Inflammatory Markers in Laparoscopic Ventral Hernia Repair

Oslo University Hospital10 enrolled

Overview

The study aims to show variation in CA-125 and other inflammatory markers assumed to be a response to trauma and peritoneal inflammation in the perioperative period of laparoscopic ventral hernia repair

CA-125 and other inflammatory markers as body temperature, CRP, PCT, leucocytes and neutrophils measured pre- and post-operatively - correlated to trauma size i.e. area of dissection, mesh size, number of fixation points etc.

Study Type

INTERVENTIONAL

Allocation

Purpose

BASIC_SCIENCE

Masking

NONE

Enrollment

Conditions

Hernia

Interventions

Laparoscopic ventral hernia repairPROCEDURE

Patients operated with laparoscopic repair of ventral or incisional hernia

Eligibility

Sex: ALLMin age: 18 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Adults admitted for ventral or incisional hernia repair Exclusion Criteria: * Loss-of-domain * ASA above III * Liver failure * Abnormal CA-125 prior to surgery

Locations (2)

Oslo University Hospital, Rikshospitalet

Oslo, Akershus, Norway

Sykehuset Innlandet HF

Gjøvik, Oppland, Norway

Outcomes

Primary Outcomes

Level of variation in inflammatory markers related to "trauma" impact

Time frame: 6 weeks post surgery

Data from ClinicalTrials.gov

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