Effects of Increased Muscle Mass on Resting Metabolic Rate

University Hospital, Linkoeping24 enrolled

Overview

Healthy males are randomized to isometric exercise for three months with either extra protein or extra calories in the form of a fast food meal/day in order to study if increase in muscle mass increases resting metabolic rate and if this is affected by presumed increased caloric intake as compared with only proteins. Body-composition was measured with Dual-Energy X-ray Absorbimetry (DEXA) and RMR was measured by registration of CO2 production and O2 consumption.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

BASIC_SCIENCE

Masking

NONE

Enrollment

Conditions

Healthy Subjects

Interventions

Isometric exercisePROCEDURE

Isometric exercise several times/week for three months

Eligibility

Sex: MALEMin age: 18 YearsMax age: 45 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: * healthy males Exclusion Criteria: * significant disease * inability to exercise

Locations (1)

University Hospital of Linkoping

Linköping, Sweden, Sweden

Outcomes

Primary Outcomes

change in resting metabolic rate

measurement of resting metabolic rate at baseline and at the end of the three month trial period

Time frame: 3 months

Secondary Outcomes

change in muscle mass

measurement of muscle mass with DEXA at baseline and at the end of the three month trial period

Time frame: 3 months

Data from ClinicalTrials.gov

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