Aerobic Interval Training in Patients With Atrial Fibrillation

Norwegian University of Science and Technology51 enrolled

Overview

The purpose of this study is to determine the effect of aerobic interval training in patients with paroxysmal or persistent atrial fibrillation, especially to see if the burden of atrial fibrillation and symptoms are reduced.

Long term endurance sport practice is associated with a higher incidence of atrial fibrillation. Moderate/light physical activity seems to be associated with a lower incidence. The underlying mechanisms are uncertain. In order to examine the effect of training in this population, the investigators will perform a randomised controlled study with aerobic interval training in patients with paroxysmal/persistent atrial fibrillation.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

PREVENTION

Masking

SINGLE

Enrollment

Conditions

Atrial Fibrillation

Interventions

Interval trainingBEHAVIORAL

Aerobic interval training will be performed with 4 times of 4 minutes intervals at an intensity of 90-95% of maximum heart rate and active pauses of 3 minutes between intervals. 3 times a week for 12 weeks.

Eligibility

Sex: ALLMin age: 18 YearsMax age: 90 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Patients with paroxysmal or persistent atrial fibrillation, that are able to perform aerobic interval training. Exclusion Criteria: * Performing high intensity training (pulse \>90% of max) for more than 2 times a week. * Moderate intensity training more than 30 min, more than 3 times a week * Previous open heart surgery * EF \<40% * Significant aorta stenosis * Mitral insufficiency, \>gr. 2 * Pacemaker * Earlier coronary intervention and not complete revascularization

Locations (1)

Norwegian University of Science and Technology

Trondheim, Trondheim, Norway

Outcomes

Primary Outcomes

Change in burden of atrial fibrillation

Burden of atrial fibrillation(number of episodes, duration(percent of the day)) continually measured, and reported by the patient. Analysed for the patients in total, with sub analysis in the groups of paroxysmal and persistent AF and in those with a low burden of atrial fibrillation vs. those with a larger burden.

Time frame: Baseline and 4 weeks after ended intervention period