The aim of the study is a medico-economic evaluation to estimate a cost differential between three modalities of Intensity-Modulated Radiation Therapy for cancers of the prostate, cervix and anal canal with pelvic lymph node irradiation : treatment with helical Tomotherapy and dynamic arc therapy using two different technologies: RapidArc or VMAT.
Study Type
INTERVENTIONAL
Allocation
NA
Purpose
OTHER
Masking
NONE
Enrollment
217
Institut Sainte Catherine
Avignon, France
Institut Bergonié
Bordeaux, France
Centre Léon Bérard
Lyon, France
Institut Paoli Calmette
Marseille, France
Assistance publique des Hôpitaux de Marseille
Marseille, France
Hôpital Clinique Claude Bernard
Metz, France
Groupe Oncorad
Montauban, France
Centre Val d'Aurelle
Montpellier, France
Centre Alexis Vautrin
Nancy, France
Institut Curie
Paris, France
...and 5 more locations
Medico-economic study : medical cost differential between 3 ways of Radiotherapy by IMRT (helical tomotherapy and dynamic arc therapy : RapidArc and VMAT).
Costs of the devices, maintenance costs ; personnel costs directly related to the medical therapeutic procedure (physicians, medical physicists, dosimetry, technicians).
Time frame: 2 months
Others economic criteria
* the estimation of the cost differential by individualizing the preparation phase and phase radiation * the analysis of the possible impact of learning in helical tomotherapy and dynamic arc therapy with VMAT and RapidArc measured on direct costs (depending on the age of implantation and equipment)
Time frame: 2 months
clinical response and safety of the treatment by radiotherapy
* Assess the skin and mucosal toxicity (acute, delayed) : CTCAEv3 * Assess the prognostic factors of onset of toxicity * Assess oncological results
Time frame: 18 Months (cervix and canal anal) or 36 months (prostate)
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