Improvement of Anorectal Function While Preserving of Inferior Mesenteric Artery Performing Left Hemicolectomy for Diverticulosis

University of Roma La Sapienza150 enrolled

Overview

The aim of the study is to evaluate the anorectal function after hemicolectomy if we preserve or not the Inferior Mesenteric Artery (IMA). This study wants to demonstrate that IMA preservation could improve patient's quality of life reducing incontinence and/or constipation rate.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

SINGLE

Enrollment

150

Conditions

Defecatory Disorders After Left Colonic or Rectal Resection

Interventions

Inferior Mesenteric Artery PreservationPROCEDURE

Performing left hemicolectomy the IMA was preserved ligating close to the colonic wall the sigmoids arteries.

Inferior Mesenteric Artery LigationPROCEDURE

Performing left hemicolectomy the IMA is ligated and sectioned after the origin of left colic artery

Eligibility

Sex: ALLMin age: 18 YearsMax age: 80 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Age from 18 to 80 years * BMI\<35 * Presence of symptomatic diverticular disease * ASA I-III Exclusion Criteria: * age \> 80 years * BMI\>35 * ASA IV * Hinchey III-IV * Past performed procedure that could be modify the nervous pattern (i.e. colorectal surgery, left nephrectomy, hysteroannessectomy)

Locations (1)

Azienda Ospedaliera Sant'Andrea

Rome, Italy, Italy

Outcomes

Primary Outcomes

Change from preoperative time in anorectal function

We evaluate the presence of modification in anorectal function respect to the preoperative time. This is assessed with specific questionnnaires and anorectal manometry

Time frame: 6 and 12 months

Secondary Outcomes

Constipation

We evaluate with a questionnaire (Constipation scoring system) the presence of postoperative constipation

Time frame: 6 and 12 months

Incontinence

We evaluate with a questionnaire (Continence scale), anorectal manometry and eventually with endoanal ultrasonography the precence of incontinence

Time frame: 6 and 12 months

Quality of life

We evaluate with SF-36 questionnaire the postoperative quality of life

Time frame: 6 and 12 months

Postoperative complication

We evaluate the presence of postoperative complication such as anastomotic leakage, anastomotic stricture, pneumonia etc.

Time frame: 1 month

Data from ClinicalTrials.gov

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