The aim of this study is to monitor the effect of intraoral topical high fluoride application on the development of white spot lesions (WSL) after orthodontic treatment with multibracket appliances and to compare it to a placebo.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
DOUBLE
Enrollment
48
1.25% fluoride (elmex® gelée) Dosage: Weekly brushing with 0.5g of respective gel Route: Intraoral topical
0% fluoride (negative control) Dosage: Weekly brushing with 0.5g Route: Intraoral topical
Poliklinik für Kieferorthopädie, Justus-Liebig-Universität Giessen
Giessen, Germany
WSL-size change
Changes in size of white spot lesions (WSL) at 12 weeks
Time frame: 12 weeks
WSL-size change
Changes in size of WSL over study time
Time frame: Baseline up to 24 weeks
WSL-brightness change
Changes in WSL brightness value (%)
Time frame: Baseline up to 24 weeks
WSL index on all upper front teeth
Modified white spot lesion index (Gorelick et al. 1982): 0: no white spot formation 1. slight white spot formation, thin rim 2. excessive white spot formation, thicker bands 3. white spot formation with cavitation
Time frame: Baseline up to 24 weeks
Caries activity
Caries activity index (LAA) according to the ICDAS II (Ekstrand et al. 2007)
Time frame: Baseline up to 24 weeks
Plaque index (Silness and Löe 1964)on all upper front teeth
The grades will be assessed visually on all upper front teeth using a standard dental probe. (0) no plaque on inspection and probing 1. thin plaque film on gingival margin, detectable only on probing 2. moderate plaque film along the gingival margin, visually detectable even without probing 3. a lot of plaque along the gingival margin, filling the interdental spaces
Time frame: Baseline up to 24 weeks
Gingival bleeding index on all upper front teeth
Gingival bleeding index (Ainamo and Bay 1975). The following scores will be used: (0) no bleeding (1) bleeding occurs
This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.
Time frame: Baseline up to 24 weeks
DMFT index: Dental health of all teeth
DMFT index according to Klein et al. (1938): Dental health of all teeth will be assessed with respect to decay (D), missing (M) or filling (F). The DMFT-Index will be calculated.
Time frame: Baseline, 24 weeks