Adjunctive Photodynamic Therapy in the Treatment of Chronic Periodontitis

Tehran University of Medical Sciences16 enrolled

Overview

The aim of this randomized clinical trial is to clinically evaluate the effectiveness of the adjunctive use of photodynamic therapy (PDT) with an light-emitting diode (LED) light source in the treatment of chronic periodontitis.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

QUADRUPLE

Enrollment

Conditions

Chronic Periodontitis

Interventions

Adjunctive Photodynamic TherapyOTHER

using Light-emitting diod(LED) (625-635nm,200mw/cm2 ,30 s for each site, fotoson CMS Dental ,Denmark) in the presence of toluidine blue O (TBO)

Light-emitting diod IrradiationOTHER

625-635nm,200mw/cm2 ,30 s for each site, fotoson CMS Dental ,Denmark

applying PhotosensitizerOTHER

toluidine blue O is applied at the bottom of each periodontal pocket

Eligibility

Sex: ALLMin age: 18 Years

Medical Language ↔ Plain English

Inclusion Criteria: 1. clinically diagnosis of advanced chronic periodontitis with more than 3 mm clinical attachment loss 2. presence of at least two teeth with probing depth of 4 to 6 mm without furcation involvement in each quadrant 3. at least 16 remaining teeth 4. no periodontal treatment in the past 12 months 5. no evidence of systemic disease related to periodontal problems 6. no use of antibiotics for the past 6 months 7. No smoking more than 10 cigarettes per day 8. no addiction to any kind of drugs 9. no pregnancy

Locations (1)

Tehran University of Medical Sciences

Tehran, Tehran Province, Iran

Outcomes

Primary Outcomes

Probing pocket depth

distance from gingival margin to base of the clinical pocket by William's periodontal probe

Time frame: Baseline, one month, three month

Secondary Outcomes

Clinical attachment loss

distance in millimeter from a fix reference point (cement-enamel junction) to the bottom of probable pocket at experimental sites

Time frame: Baseline, one month, three month

Bleeding upon probing

presence or the absence of bleeding up to 30 second after probing with a William's periodontal probe

Time frame: Baseline, one month, three month

plaque index

teeth number 16,12,24,36,32,44 are evaluated according to silness plaque index instruction were scored between 0 to 3

Time frame: Baseline,before PDT procedure, one month, three month

Data from ClinicalTrials.gov

This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.