Efficacy of Intraoperative Surgical Scrubbing in Reducing Bacterial Load After Nail Removal Surgery

Universidad Complutense de Madrid50 enrolled

Overview

The investigators conducted a controlled, prospective randomized study to examine the antiseptic efficacy of intraoperative irrigation methods during nail avulsion surgery.

The investigators conducted a controlled, prospective randomized study to examine the antiseptic efficacy of intraoperative scrubbing methods during nail avulsion surgery. The investigators compared intraoperative antiseptic scrubbing using 0.9% saline solution and 0.1% polihexanide. Swab samples were taken from each patient at 5 distinct stages throughout the surgical procedure, and bacterial culture analysis was performed (positive culture rate, total inocula count, reduction of bacterial load, and identification of specific microorganisms).

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

PREVENTION

Masking

NONE

Enrollment

Conditions

Skin Diseases Nail Diseases Nails, Ingrown

Interventions

PolihexanideDRUG

The investigators compared intraoperative antiseptic irrigation using 0.9% saline solution and 0.1% polihexanide.

Eligibility

Sex: ALLMin age: 18 YearsMax age: 80 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Older than 18 * Onychocryptosis Exclusion Criteria: * infection * a history of tinea pedis * onychomycosis * paronychia * nail trauma or subungual hematoma * nail deformities and disorders * peripheral vascular disease or diabetes * cardiac disease * a history of rheumatic fever * recent antibiotic use or current antimicrobial therapy * a history of steroid use and * recent nail polish use

Locations (1)

Universidad Complutense de Madrid

Madrid, Madrid, Spain

Outcomes

Primary Outcomes

bacterial count (CFU/cm2)

The percentage of inoculum reduction at the irrigation step was calculated as follows: percentage of inoculum reduction = 100 e (1003 Ii)/Is, where Ii is the bacterial count (CFU/cm2) at the irrigation step and Is is the inoculum (CFU/cm2) at the surgery step. Bacteria were identified using standard laboratory methods. The limit of detection in the nailfold test was 1.33 CFU/cm2.

Time frame: Participants will be followed until the surgery to heal completely,an expected average of 7 weeks

Data from ClinicalTrials.gov

This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.