To show whether the artery first approach leads to equal or less rate of positive resection margins in pancreatic head cancer than the standard technique (ppWhipple only with standard Kocher's manoeuvre)
This is a prospective non-randomized trial with two study groups. The trial is designed to show if the ARTERY FIRST approach reduces the rate of R1 resections in patients undergoing surgery for cancer of the pancreatic head. After the diagnosis of cancer of the pancreatic head by clinical, laboratory and imaging evaluation patients who are scheduled for resection will be screened for inclusion into the trial. Informed consent is obtained at least on the day before surgery and patients meeting the eligibility criteria will be enrolled into the study.
Study Type
INTERVENTIONAL
Allocation
NON_RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Enrollment
124
early identification of SMA to evaluate infiltration
conventional exposure and preparation (Kocher's manoeuvre) before transection of pancreatic parenchyma
Department of General, Visceral and Transplantation Surgery, University of Heidelberg
Heidelberg, Baden-Wurttemberg, Germany
RECRUITINGRate of R1 resections
positive resection margins as described by the pathologists of the University of Heidelberg
Time frame: up to 1.5 years
Exploratory analyses
Exploratory analyses of frequencies of complications and serious adverse events
Time frame: up to 1.5 years
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