Impact on Cognitive Function and Quality of Life of Adjuvant Chemotherapy in Patients Aged Over 65 Years: Application to Breast Cancer or Colon

Inclusion Criteria for patients with chemotherapy : * Patient(e) aged over 65 years * Non metastatic breast cancer * Adjuvant chemotherapy Breast cancer: FEC, including Docetaxel Protocols * No major cognitive impairment * Lack of personality disorders and psychiatric disorders evolutionary * Having signed the informed consent of study participation Inclusion Criteria for patients without chemotherapy (control group): * Patient(e) aged over 65 years * Breast cancer * Patients receiving no adjuvant chemotherapy * No major cognitive impairment * Lack of personality disorders and psychiatric disorders evolutionary * Having signed the informed consent of study participation * Matching on age, sex, cultural level and tumor location Exclusion Criteria for patients with chemotherapy : * Metastatic * Cancer primitive other than breast * Patients under 65 years * Patients with adjuvant chemotherapy is associated with targeted therapy * Patients who have received other cancer treatments (chemotherapy or radiotherapy brain) * disorders of higher functions existing in the administration of chemotherapy * Pathology psychiatric evolutionary * Refusal of participation * Patients unable to meet the cognitive tests * Drug use * Heavy drinking