The purpose of this study is to demonstrate the safety and immunogenicity of an oral vaccine to prevent avian influenza. Volunteers will receive either one or two doses of research vaccine or placebo as part of this study.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
PREVENTION
Masking
QUADRUPLE
Enrollment
54
adenovirus with the dsRNA adjuvant, dried and put into capsules
Capsules of the same size and shape as experimental groups
Unnamed facility
San Diego, California, United States
Frequency or severity of vaccine related events as measured through reported AEs
Time frame: up to 1 year
Magnitude of humoral immune responses to avian influenza as measured by functional assays
Time frame: up to 1 year
Magnitude of cellular immune responses to avian influenza as measured by functional assays
Time frame: up to 1 year
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