Psychometric Validation of Cognitive Endpoints

Inclusion Criteria: * 18 to 65 years old (inclusive). * History of Relapsing-Remitting or Secondary Progressive Multiple Sclerosis * Physically able to see the testing materials and complete the tests * Have a family member or caregiver who is capable of consent and willing to complete the MSNQ-Informant questionnaire. Exclusion Criteria: * A history of treated or untreated severe mental illness or diagnosis of major depression prior to MS onset. * Untreated major depression or untreated anxiety disorder. * History of Attention Deficit/Hyperactivity Disorder, Developmental Learning - Disorder including Mental Retardation. * History of traumatic brain injury with intracranial bleed, stroke, Alzheimer's disease, Parkinson's disease, Motor Coordination Disorder or other neurologic illness. I understand that if the Investigator believes this would interfere with successful completion of the protocol, I will be excluded. * A clinically significant relapse within the past 2 months. I have had a serious infection (e.g., pneumonia, septicemia) within the 2 month. * History of drug or alcohol abuse (as defined by the Investigator) within 1 year prior to Study Day 1. * Active bacterial or viral infection. * Use of marijuana within 2 months prior to Study Day 1or at any time during the study * Alcohol consumption within 24 hours of either test session. * Unable to comply with study requirements. * Expected survival time of less than 3 months.