The purpose of the study is to examine the relevance of biochemical markers (specific pulmonary and cardiac markers and markers of endogenous stress) in the process of weaning in patients with artificial ventilation.
Artificially ventilated patients on our intensive care unit will be monitored if specific biomarkers have a relevance in risk stratification, optimizing therapy, outcome and success in the process of weaning. Therefore, consecutively, specific blood parameters will be taken at time of intubation,day 1 of weaning and extubation.
Study Type
OBSERVATIONAL
Enrollment
100
Intensive Care Unit, University of Heidelberg
Heidelberg, Baden-Wurttemberg, Germany
RECRUITINGsuccess of weaning
primary outcome measure is the success of weaning during hospital stay. Duration of hospital stay is estimated between 1-60days, in average 30days. Criteria is spontaneous breathing.
Time frame: participants will be followed for the duration of hospital stay, an expected average of 30days
follow up
Follow up is done after 12 months to check major adverse cardiac or pulmonary events (death, myocardial infarction, re-hospitalisation)
Time frame: 12 months
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