The Effect of Metformin on the Correlation Between Hyperinsulinemia and Hypertension

China-Japan Friendship Hospital140 enrolled

Overview

The objective of this study is to investigate the effect of metformin on the correlation between hyperinsulinemia and hypertension.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

NONE

Enrollment

140

Conditions

Diabetes Mellitus Essential Hypertension

Interventions

FosinoprilDRUG

Fosinopril group received fosinopril, 10mg, once per day.

MetforminDRUG

Metformin group was treated with metformin hydrochloride, 500mg, three times per day

Eligibility

Sex: ALLMin age: 20 YearsMax age: 65 Years

Medical Language ↔ Plain English

Inclusion Criteria: * 20 to 65 years of age, regardless of sex * duration of hypertension was \<5 years * overweight or obesity, mild to moderate hypertension, receive no euglycemic agent or antiobesity drug

Outcomes

Primary Outcomes

Blood pressure measurement

Time frame: 8 weeks

Data from ClinicalTrials.gov

This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.