Prolactinoma is the most prevalent anterior hypophysis tumor. The principal treatment for this disorder is Dopamine agonist drugs including bromocriptin and Cabergoline. However, 50% of Bromocriptin treated and 17% of Cabergoline treated patients are resistant to these drugs. Curcumin is the main derivative of turmeric ,an old spice which is used frequently in Indian and Iranian cuisine. It has been proved that curcumin can reduce mammotrope cells proliferation and also intracellular hormone production. The purpose of this study is to evaluate the effect of turmeric on prolactinoma patients.
Study Type
INTERVENTIONAL
Allocation
NA
Purpose
TREATMENT
Masking
NONE
Enrollment
30
Curcumin is prescribed to new cases of hyperprolactinoma
Mashad University of Medical Sciences
Mashhad, Khorasan Razavi, Iran
RECRUITINGserum prolactin level
Time frame: 2weeks and one month after treatment
change in LH,FSH and estradiol from baseline
Time frame: one month ofter treatment
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