Epicardial Fat, Visceral Fat and Coronary Atherosclerosis

Inclusion Criteria: * Patients referred to cardiac CT will be the source of recruitment. * patients with excess of visceral fat, * 30 patients with liver fat accumulation * 30 sex-age-matched individual (controls) will be enrolled. All patients will undergo a complete family history, personal clinical history, physical examination and blood sampling for biochemical analysis. * Informed consent will be obtained from each individual. Exclusion Criteria: * subjects with severe morbid obesity (body mass index \[BMI\] \> 40), * recent history of acute illness, * clinical history of ischemic heart disease and cerebrovascular disease, * typical chest pain, * previous coronary artery disease, * conventional coronary angiography, percutaneous interventions, coronary by pass grafting, renal failure, cancer patients, * subjects who take drugs that induces hepatic steatosis ( corticosteroids, estrogens, methotrexate, amiodarone and others)