A Study of Administration of Trastuzumab (Herceptin) by a Single-use Injection Device Versus a Handheld Syringe

Inclusion Criteria: * Healthy male patients, 18 to 45 years of age, inclusive * No history of hypersensitivity or allergic reactions following drug administration * No history of clinically significant or clinically relevant cardiac condition * No history of previous anticancer treatment * Body mass index (BMI) between 18-32 kg/m2, inclusive Exclusion Criteria: * Positive test result for drugs of abuse * Positive test result for hepatitis B, hepatitis C, or HIV 1 or 2 * Systolic blood pressure greater than 140 mmHG or less than 90 mmHG, or diastolic blood pressure greater than 90 mmHG or less than 50 mmHG * Clinically significant abnormal laboratory values