A Study on the Effect of Food on the Pharmacokinetics of RO5428029 in Healthy Volunteers

Inclusion Criteria: * Healthy volunteers, 18 to 60 years of age inclusive * Body mass index (BMI) between 18 and 29.9 kg/m2, inclusive, and a minimum weight of 45 kg * Female subjects must be surgically sterile or post-menopausal * Male subjects and their partners of child-bearing potential must use 2 methods of contraception (one of which a barrier method) for the duration of the study and for at least 70 days after the last dose Exclusion Criteria: * Pregnant or lactating women, and male partners of women who are pregnant or lactating * Women with reproductive potential * History (within 3 months of screening) of alcohol consumption exceeding 2 standard units per day on average; alcohol consumption will be prohibited at least 48 hours before screening * Positive test for drugs of abuse * History or symptoms of any significant disease * Positive for HIV, hepatitis B or hepatitis C infection * Participation in an investigational drug or device study within 3 months prior to screening