Clinical Trial of Zirconia and Metal Adhesive Bridges

Queen Mary University of London

Overview

Adhesive bridges are becoming popular in patients with congenitally missing teeth and these are type of bridges that can be done with only minimal or with no preparation to replace the missing tooth/teeth. The best clinical gain is the minimal tooth preparation or no need for the removal of tooth substance. Treatment for this type of bridges does not usually require anaesthesia. In addition, adhesive bridges can provide reasonable aesthetical outcome with minimal cost and reduced chair time. The biggest issue is that high failure rate in the long term, and gray colour shining through the metal wing cemented onto the abutment tooth. This can compromise the aesthetical outcome. The aesthetical problem can be solved by the use of zirconia all ceramic material to construct the bridge.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

OTHER

Masking

NONE

Conditions

Missing Teeth

Interventions

Zirconia-based adhesive bridgePROCEDURE

Zirconia-based adhesive bridge will be used to replace the missing tooth/teeth.

Metal-based adhesive bridgePROCEDURE

The metal-based adhesive bridge will be used to replace the missing tooth/teeth.

Eligibility

Sex: ALLMin age: 18 YearsMax age: 80 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: * Male or female ≥ 18 years of age * Has a maximum of 2 units requiring placement * Is a regular dental attendee and agree to return for assessments * Written subject informed consent (IC) for this protocol will be obtained prior to study enrolment. Each subject will be required to sign and date the IC form prior to their participation * Sound or minimally restored abutment(s) Exclusion Criteria: * The presence of any periodontal pocket depths equal or above 4 mm with active periodontal disease * Any history of adverse reaction to clinical materials to be used in this study * They are pregnant or had serious medical condition that may interfere with the dental treatment * Acquired tooth loss more than 2 units requiring replacement * Participants who have parafunctional habits * Severe Class II Div II cases

Locations (1)

Barts and The London, School of Medicine and Dentistry

London, United Kingdom

Outcomes

Primary Outcomes

Clinical survival of adhesive bridges

Evaluation of clinical survival: participants will be evaluated according to the modified USPHS criteria. The evaluation criteria will include: retention, framework fracture, veneering fracture, marginal adaptation, recurrent caries and colour match. The examination will be after one to two weeks, after 3, 6, 9, 12 and 18 months, 2, 3, 4 and 5 years. The evaluation will also include the biological complication. Plaque, gingival index, periodontal probing depth and gingival recession will be evaluated around the abutments and compared to a control tooth

Time frame: 5 Years

Secondary Outcomes

Quality of life, aesthetic outcome.

The patients will be requested to fill the OHIP-14 and the VAS questionnaires after one week to two weeks, after 3, 6, 9, 12 and 18 months in order to assess the quality of their lives and their aesthetic outcome after having the bridge.

Time frame: 18 months

Marginal discrepancy evaluation.

Marginal discrepancy will be evaluated by means of Scannining Electron Microscope (SEM) after cementation.

Time frame: After cementation

Economic evaluation

Economic evaluation will be run in parallel to the study and will include the overall cost of the two treatments.

Time frame: 5 years

Data from ClinicalTrials.gov

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