Absorption, Distribution, Metabolism and Excretion (ADME) Study With Single Oral Administration of [14C] NKTR-118

Inclusion Criteria: * Have a body mass index (BMI) of ≥18 and ≤30 kg/m2 and a minimum weight of 50 kg * Regular daily bowel movements (ie, production of at least 1 stool per day). * Non-smoker or ex-smoker who has not used tobacco or nicotine products for ≥3 months prior to Visit 1 Exclusion Criteria: * Healthy volunteers who have been exposed to radiation levels above background (eg, through X-ray examination) of \>5 mSv in the last year, \>10 mSv in the last 5 years, or a cumulative total of \>1 mSv per year of life * Participation in any prior radiolabelled study within 12 months of screening visit 1 * Excessive intake of caffeine containing drinks e.g., coffee, tea, caffeine containing energy drinks and cola (more than 5 cups of coffee or equivalent per day