Underinflation and overinflation of tracheal cuff are common in intubated patients, including those intubated with polyurethane-cuffed tubes. The aim of this study is to determine the efficiency of a pneumatic device in controlling cuff pressure.
Underinflation and overinflation of tracheal cuff are associated with severe complications such as microaspiration of contaminated secretions, and tracheal ischemia. Efficient control of cuff pressure would probably allow reducing complications related to variations in cuff pressure.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Enrollment
64
Continuous control of cuff pressure using a pneumatic device (Nosten) Cylindrical (Kimberly Clark tube) or tapered (Covidien tube) tracheal cuff
ICU, Calmette Hospital, CHU de Lille
Lille, Nord, France
Percentage of patients with underinflation or overinflation of cuff pressure
Continuous recording of cuff pressure will be performed during 2 24-h periods (with or without the pneumatic device)
Time frame: 48 h
Impact of tracheal-cuff shape on variations in cuff pressure
Patients will be intubated with cylindrical or tapered polyurethane cuffed tubes.
Time frame: 48 h
Impact of continuous control of cuff pressure on microaspiration of gastric contents
Pepsin will be quantitatively measured in tracheal aspirates of all patients during the 2 24-h periods (with or without the pneumatic device)
Time frame: 48 h
Impact of tracheal cuff shape on microaspiration of gastric contents
Pepsin level in tracheal aspirates will be compared between patients intubated with cylindrical polyurethane cuffed-tubes versus those intubated with tapered polyurethane cuffed-tubes
Time frame: 48 h
This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.