Effect of Arotinolol Hydrochloride on Cardiovascular Events in Hypertensive Haemodialysis Patients

Inclusion Criteria: * Aged between 18-75 years-old; * Chronic kidney disease stage 5 with haemodialysis treatment for 2 months; * Patients with blood pressure≥140/90 mmHg after receiving 2 or 3 antihypertensive medications for 2 weeks; * Patients who receiving alfa or beta blockers will be washed out for 2 weeks; * Written informed consent Exclusion Criteria: * Unstable angina, myocardial infarction, symptomatic or continuous arrhythmia, cardiosurgery in the last 2 months; * Patients who taking class I antiarrhythmic drugs; * Resting heart rate less than 60; * Patients with systolic pressure less than 90 mmHg; * Patients with chronic obstructive pulmonary disease and asthma; * Patients with cerebral infarction in the last 2 weeks; * Severe disorders of liver function; * Allergy to the arotinolol; * Patients who planning to have kidney transplantation in the near future; * Pregnancy and breast-feeding; * Malignant tumor