Effects of Lactobacillus Delbruckii Lactis DN111244 Fermented Milk Consumption on Plasma Lipids Levels in Hypercholesterolaemic Adults

Inclusion Criteria: * male and female aged 18-75 years; * BMI between 19 and 30 kg/m2, * LDL-cholesterol plasma level between 130 mg/dL to 190 mg/dL (bounds included) with or without statin monotherapy, * stabilized hypercholesterolemia (since more than 3 months), * accepting to follow the dietary recommendations advisable for hypercholesterolemic patient (NCEP-ATP III guidelines), * used to consume dairy products, * for female: effective contraceptive methods used, * agreeing to a written informed consent Exclusion Criteria: * plasma triglycerides (TG) levels \> 350 mg/dL (4 mmol//L), * any cardiovascular event (infarction, angina, surgical or endocoronary intervention, stroke, peripheral arteriosclerosis, etc) in the last 6 months, * known allergy or hypersensitivity to milk proteins, * systemic treatment or topical treatment likely to interfere with evaluation of the study parameters, * subject currently involved in a clinical trial or in an exclusion period following participation in another clinical tria, * subject in a situation which in the investigator's opinion could interfere with optimal participation in the present study or could constitute a special risk for the subject, * diabetic subjects (type I and type II), * any kind of disease likely to interfere with the evaluation of efficiency or safety of the product, * for female subject: pregnancy, breast feeding or intention to become pregnant during the study, * for female subject: subject likely to change her contraceptive method during the study, * active heavy cigarette smokers (reported more than 20 cigarettes / day), * subjects who are actively participating in a weight loss program or have participated in a weight loss program in the three months prior to screening for the study