Effect of Vitamin A Supplementation on Iron Metabolic Homeostasis of Preschool Children in Sichuan,China

Chengdu Maternal and Children's Health Care Hospital450 enrolled

Overview

The investigators plan to perform a randomized, mutual-control and double-blinded cohort study to further exploit the vitamin A supplementation on iron metabolic homeostasis (including iron reserve, mobilization and absorption status in the same population) compared with solely iron and vitamin A plus iron.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

PREVENTION

Masking

QUADRUPLE

Enrollment

450

Conditions

Iron Metabolic Homeostasis

Interventions

iron and vitamin aDRUG

Eligibility

Sex: ALLMin age: 2 YearsMax age: 6 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: * apparent health; * Hb concentration\>60 g/L; * C-reaction protein (CRP)\<10 mg/L; * parental or guardian approval of participation in all aspects of the study; and * parental/guardian agreement to avoid the additional use of vitamin and mineral supplements during the investigation. Exclusion Criteria: * does not match the inclusion criteria

Outcomes

Primary Outcomes

hemoglobin

Time frame: 6 months

hemoglobin

Time frame: six months

Data from ClinicalTrials.gov

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