Effect of Hemodialysis Membranes on Platelet Count

Northwell Health99 enrolled

Overview

The purpose of this study is to determine if there is a drop in platelet count after hemodialysis. Hemodialysis membranes are known to activate complement and cause a drop in platelets and sometimes in white blood cells. The investigators are going to study one of the membranes which is the Fresenius Optiflux® to check if it causes a drop in platelets.

Study Type

OBSERVATIONAL

Enrollment

Conditions

Thrombocytopenia

Eligibility

Sex: ALLMin age: 18 YearsMax age: 90 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Patients on Hemodialysis for \>=6 months Exclusion Criteria: * Hematological Cancers * Myelodysplastic syndromes * Baseline thrombocytopenia * Acute infections (patients on antibiotics) * Patients with Immune thrombocytopenic purpura (ITP)/Thrombotic thrombocytopenic purpura (TTP) * HIV * Liver disease

Locations (1)

Island Rehabilitative Service

Staten Island, New York, United States

Outcomes

Primary Outcomes

Drop in platelet counts

Time frame: 90 minutes through hemodialysis and immediately after finishing hemodialysis

Data from ClinicalTrials.gov

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