Cough is the most bothersome symptom for patients with the common cold. The objective of the study is to compare the phytotherapic "Bromelin", a compound preparation of honey from the bee apis mellifera with the extract of the pineapple (Ananas comosus) with placebo in reducing cough episodes in patients with the common cold.
Common cold is very frequent and cough is one of the most troublesome symptoms. Over-the-counter medications are used by patients without prescription, many times with important side effects. Bromelin, a compound made with honey and pineapple extract could offer cough symptomatic relief as a soothing agent. This study aims to compare this compound with placebo in reducing cough in patients with common cold in an clinical trial designed in conformity to CONSORT guidelines.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
DOUBLE
Enrollment
102
Hospital das Clínicas/UFPE
Recife, Pernambuco, Brazil
RECRUITINGChange in score in a cough evaluation questionnaire
A cough score based on number of coughing episodes and subjective 5 item cough score : no cough, mild, moderate, severe, very severe.
Time frame: before and 10 and 30 minutes after the dosing
Change in Occurrence of gastric symptoms
Question "YES" as answer to questions about gastric symptoms as nausea and/or vomiting after medication
Time frame: 10 and 30 minutes
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