Clinical Trial To Evaluate ANT-1207 In Subjects With Crow's Feet

Anterios Inc.111 enrolled

Overview

The purpose of this study is to provide evidence of the safety, tolerance, and efficacy of ANT-1207 in the treatment of Crow's Feet.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

QUADRUPLE

Enrollment

111

Conditions

Lateral Canthal Lines Crow's Feet

Interventions

ANT-1207BIOLOGICAL

The interventions differ by dose of investigational product applied.

Botulinum Toxin, Type ABIOLOGICAL

The interventions differ by dose of investigational product applied.

Botulinum Toxin Type ABIOLOGICAL

The interventions differ by dose of investigational product applied.

Eligibility

Sex: ALLMin age: 30 YearsMax age: 70 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: * mild to moderate Crow's Feet wrinkles (IGA 2-3) at rest * moderate to severe Crow's Feet (IGA 3-4) on contraction * willingness to refrain from any product affecting skin remodeling * female subjects must be not pregnant and non-lactating Exclusion Criteria: * history of peri-ocular surgery, brow lift or related procedures * procedures affecting the lateral canthal region in the prior 12 months * application of topical prescription medication to the treatment area * female subjects who are pregnant or are nursing a child

Locations (6)

Total Skin & Beauty Dermatology Center

Birmingham, Alabama, United States

Baumann Cosmetic & Research Institute

Miami Beach, Florida, United States

Palm Beach Esthetic Dermatology and Laser Center

West Palm Beach, Florida, United States

William Coleman III, MD, APMC

Metairie, Louisiana, United States

Outcomes

Primary Outcomes

Efficacy will be assessed by Investigator's Global Assessment Score

Wrinkle scale with definitions of severity

Time frame: 2 weeks

Secondary Outcomes

Subject Self Assessment (SSA) scale

Change from Baseline in the Subject Self Assessment scale

Time frame: 2 Weeks

Investigator Global Assessment scale

Change from Baseline in wrinkle scale assessment at all other timepoints

Time frame: Week 1, 2, 4, 8, 12

Data from ClinicalTrials.gov

This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.