Feasibility of Imaging in the Treatment of Patients With Advanced Head and Neck Cancer

Inclusion Criteria: * Treatment naive patients with histologically proven cancer of the head and neck * T4 primary tumor (all sites), N2 or N3 locoregional disease (all sites) * At least one measurable site of disease * At least 18 years of age * Karnofsky performance status \> or = 70% or ECOG \<2 * Able to tolerate SPECT/CT imaging * Adequate bone marrow function * Adequate liver function * Adequate renal function * Written consent from patients * Female patients of childbearing potential must have a negative pregnancy test within 0-7 days prior to the first SPECT study Exclusion Criteria: * Diabetics with insulin dependence or blood sugar levels \>200 mg/dL prior to imaging * Patient weight above the SPECT/CT table weight limit * Pregnant and/or lactating female * Unequivocal demonstration of metastatic disease * Patients unwilling to or unable to comply with protocol