Evaluation of the Oncoral® Test in Epidermoid Carcinomas of the Upper Aerodigestive Tract

Inclusion Criteria: First step: * Man or woman aged more than 40 years * With frequent alcohol intoxication and/or smoking * With histologically confirmed epidermoid carcinoma of the upper aerodigestive tract * No treatment delivered for this disease * Signed, written informed consent * Mandatory affiliation with a health insurance system Second step: * Man or woman aged more than 40 years * With frequent alcohol intoxication and/or smoking * With no sign of an epidermoid carcinoma of the upper aerodigestive tract * Signed, written informed consent * Mandatory affiliation with a health insurance system Exclusion Criteria: First step: * Previous history of cancer except carcinoma in situ of the uterine cervix or skin basal cell carcinoma treated with curative intent * Gingivorrhagia when the test is realised * Hypersensitivity to aspirin or to benzoate * Asthmatic, diabetic patients or patents with chronic bronchitis requiring oxygen therapy * Patients taking antibiotics at enrolment or during the previous week Second step: * Previous history of cancer except carcinoma in situ of the uterine cervix or skin basal cell carcinoma treated with curative intent * Patient already treated for a cancer * Gingivorrhagia when the test is realised * Hypersensitivity to aspirin or to benzoate * Asthmatic, diabetic patients or patients with chronic bronchitis requiring oxygen therapy * Patients on antibiotics at enrolment or during the previous week