Neoadjuvant Chemotherapy Versus Radiochemotherapy for Cancer of the Esophagus or Cardia

Inclusion Criteria: * Histologically verified squamos cell carcinoma, adenocarcinoma of the esopohagus or gastric cardia (type II) * Tumor located in cervical oesophagus, not requiring laryngo-esophagectomy. Patients with performance status 0-1 axxording to WHO scale and with resectable tumours, as assessed at the prerandomisation evaluation * Adequate haemotological function, defined as having WBC \> 3 x 10(9)/litre and platelets \> 100 x 10 (9)/litre. * Adequate renal function defined as having normal serum creatinine level and/or calculated glomerular filtration rate \> 60 ml/min. * Tumour stage: T1Ni, T2N0, T2N1, T3N0, T3N1, M1a Exclusion Criteria: * Pregnancy and/or lactation. Women of childbearing ages can be included and provided that adequate contraceptive methods are used * Patients with diabetes complications (e.g. rethinopathy, neuropathy) as well as patients with uncontrolled cardiac disease or myocard infarction within 12 months are considered unsuitable for chemoradiotherapy. * Concomitant malignancy (\< 5 years since diagnosis) that can interfere the interpretation of study results, ongoing antitumoral treatment. * Patients being unable tom comply with the protocol * Tumor stage T1 N0, T4 NX or TXNXM1b