Study About Predicting Fluid Responsiveness in Children Undergoing Neurosurgery

Seoul National University Hospital33 enrolled

Overview

The purpose of this study is to evaluate static and dynamic parameters, echocardiographic parameters, and pleth variability index for predicting fluid responsiveness in children. Children who need volume expansion will receive colloid 10 mL/kg. Blood pressure, heart rate, central venous pressure, systolic pressure variation, pulse pressure variation, delta down, aortic blood flow velocity variation, inferior vena cava diameter variation, and pleth variability index will be measure before and after volume expansion. Patients will be classified as responders to volume loading if stoke volume index increase by at least 15%.

Study Type

INTERVENTIONAL

Allocation

Purpose

DIAGNOSTIC

Masking

SINGLE

Enrollment

Conditions

Fluid Responsiveness

Interventions

fluid loading of 10 mL/kg colloid (voluven)

Eligibility

Sex: ALLMax age: 8 Years

Medical Language ↔ Plain English

Inclusion Criteria: * neurosurgery under general anesthesia * \< 8 years old Exclusion Criteria: * cardiac disease * pulmonary, renal and hepatic disease * infectious disease * hematologic and muscular disease

Locations (2)

Seoul national university hospital

Seoul, South Korea

Seoul national university hospital

Seoul, South Korea

Outcomes

Primary Outcomes

stoke volume index

Volume loading will be performed for 20 minutes. Stroke volume will be meausred before and after volume expansion

Time frame: before and after volume loading (20 minutes)

Data from ClinicalTrials.gov

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