The purpose of this research is to evaluate the effectiveness of ketamine as an analgesic adjuvant in decreasing the narcotic (opioids) analgesics during surgery, on pain management and on the later recovery after surgery in patients undergoing colorectal surgery.
Adjuvant is a drug that has few or no pharmacological effects by itself, but may increase the effectiveness or strength of other drugs when given at the same time.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
TRIPLE
Enrollment
21
Loading and Infusion: Saline at infusion rate calculated and adjusted for weight to match ketamine bolus-infusion rate
Loading: 1 mg/Kg Infusion: 10 mcg/kg/min
Loading: 0.5 mg/Kg Infusion: 5 mcg/kg/min
Cedars Sinai Medical center
Los Angeles, California, United States
Number of Participants With Opioid Consumption
Perioperative use of opioid consumption at Post Anesthesia Care Unit (PACU) Data obtained from patient charts
Time frame: 1 day
Postoperative Pain
Postoperative pain was measured at PACU using a Verbal Rating Scale (VRS) from 0 to 10 with 0 representing "no pain" and 10 "very much pain.
Time frame: one day
Participants With Nausea and Vomiting at PACU
Postoperative nausea and vomiting at PACU Participants experiencing nausea and/or vomiting.
Time frame: 1 day
This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.