Biomarker in Tissue Samples From Patients With Ewing Sarcoma

Children's Oncology Group40 enrolled

Overview

RATIONALE: Studying samples of tissue from patients with cancer in the laboratory may help doctors learn more about changes that occur in DNA and identify biomarkers related to cancer. PURPOSE: This research trial studies biomarkers in tissue samples from patients with Ewing sarcoma.

OBJECTIVES: * To determine the frequency of INI-1 protein loss in Ewing Sarcoma. OUTLINE: Previously collected tissue samples are analyzed for INI-1 protein loss by IHC and tissue microarray.

Study Type

OBSERVATIONAL

Enrollment

Conditions

Sarcoma

Interventions

microarray analysisGENETIC

protein analysisGENETIC

immunohistochemistry staining methodOTHER

laboratory biomarker analysisOTHER

Eligibility

Sex: ALLMax age: 120 Years

Medical Language ↔ Plain English

DISEASE CHARACTERISTICS: * Diagnosis of Ewing sarcoma * Prepared tissue microarray with Ewing sarcoma samples available PATIENT CHARACTERISTICS: * Not specified PRIOR CONCURRENT THERAPY: * Not specified

Outcomes

Primary Outcomes

Frequency of INI1 protein loss in Ewing Sarcoma

Data from ClinicalTrials.gov

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