Gut Hormones After Meal Ingestion in Males Versus Females

Lund University24 enrolled

Overview

The study hypothesis is that the release of gut hormones is increased proportionally to caloric load in each meal. Three different meals with different meal size will therefore be served and gut hormones determined.

In healthy males and females, meals with 511, 743 and 1034 kcal will be given orally. Samples will be taken during the following 300 min and gut hormones (glucose-dependent insulinotropic polypeptide and glucagon-like peptide-1) will be determined along with insulin and glucagon levels.

Study Type

INTERVENTIONAL

Allocation

NON_RANDOMIZED

Masking

NONE

Enrollment

Conditions

Normal Non-fluency

Interventions

Meal ingestionOTHER

Meal 511 kcal, meal 743 kcal or meal 1034 kcal

Eligibility

Sex: ALLMin age: 20 YearsMax age: 30 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: * Healthy status Exclusion Criteria: * Diabetes * Liver disease * kidney disease * thyroid disease

Locations (1)

Department of Clinical Sciences Lund, Lund University

Lund, Sweden

Outcomes

Primary Outcomes

Release of gut hormones

Time frame: 300 min

Secondary Outcomes

Insulin secretion

Time frame: 300 min

Data from ClinicalTrials.gov

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