This study is to explore the clinical efficacy of continuous Endostar infusion combined with radiotherapy in esophageal cancer patients.
Study Type
INTERVENTIONAL
Allocation
NA
Purpose
TREATMENT
Masking
NONE
Enrollment
40
75mg Endostar in 235mL normal saline, 24h continuous infusion, 6 weeks
6~15MV X-ray, 2Gy/time,5times/week,6 weeks
The First People's Hospital of Lianyungang
Lianyungang, Jiangsu, China
RECRUITINGObjective Response Rate (ORR)
Time frame: 1 month after treatment
Overall Survival (OS)
Time frame: 2 years
Time to Progression (TTP)
Time frame: every three months until disease progression
Clinical Benefit Rate (CBR)
Time frame: 1 month after treatment
Serum VEGF Levels
Time frame: at baseline and 6 weeks
Incidence of Adverse Events
Time frame: up to 3 months
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