Perceived Barriers to Patient Adherence After Pediatric Solid Organ Transplantation

National Institute of Allergy and Infectious Diseases (NIAID)502 enrolled

Overview

In this study, doctors will observe how and when pediatric patients who have received a solid organ transplant take their prescribed medication, and determining if there are reasons that keep these patients from taking all of their medicine.

Adhering to treatment regimens after solid organ transplantation is critical for the prevention of complications, including acute and chronic organ rejection. It is important to recognize the perceived barriers to following treatment regimens and identify ways to address these barriers early in the course of treatment.

Study Type

OBSERVATIONAL

Enrollment

502

Conditions

Organ Transplantation

Eligibility

Sex: ALLMax age: 21 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Subject and/or guardian must be able to understand and provide informed consent/assent in English or Spanish * Male or female primary solid organ transplant patients 0-21 years of age * Recipients at least 1 month post-transplant hospital discharge Exclusion Criteria: * Inability or unwillingness of a participant or parent/guardian to give informed consent or comply with study protocol * Condition or characteristic which in the opinion of the investigator makes the participant unlikely to complete the questionnaires * Re-transplant recipient * Multi-organ transplant recipient

Locations (15)

University of Alabama

Birmingham, Alabama, United States

Ronald Reagan UCLA Medical Center (Mattel Childrens')

Los Angeles, California, United States

Outcomes

Primary Outcomes

Perceived barriers to adherence in adolescents and parent/legal guardian of pediatric patients

Barriers assessed using Brief Medication Questionnaire (BMQ); Adolescent Medication Barrier Scales questionnaire (AMBS); and Parent Medication Barriers Scale questionnaire (PMBS)

Time frame: 1 month post transplant

Change in perceived barriers to adherence from baseline to follow-up

Barriers assessed using Brief Medication Questionnaire (BMQ); Adolescent Medication Barrier Scales questionnaire (AMBS); and Parent Medication Barriers Scale questionnaire (PMBS)

Time frame: 12 months post transplant

Data from ClinicalTrials.gov

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