Brain SPECT Following Cialis (Tadalafil ) Administration

Wolfson Medical Center30 enrolled

Overview

The study will be an open label one and will include 30 patients who underwent ischemic stroke 3 month to 3 years prior to the study. All patients will undergone a baseline brain SPECT perfusion study. 15 patients will take one dose of 20 mg cialis, and will have a second brain SPECT 24 hours after cialis administration. 15 other patients (age and risk factor matched) will be prescribed 5 mg of cialis once daily for 7 days, and a second SPECT study will be performed 24 hours after the last dose.

Study Type

OBSERVATIONAL

Enrollment

Conditions

Change in Brain Perfusion

Eligibility

Sex: ALLMin age: 35 YearsMax age: 80 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Male and female patients in the age range of 35-75 years. Exclusion Criteria: 1. known allergic reaction to TF 2. Medical contraindication to use TF 3. Hemorrhagic stroke including intracerebral hemorrhage and subarachnoid hemorrhage 4. Acute stroke or cardiac ischemic event up to 3 month prior to study. 5. Other neurological brain diseases including degenerative diseases, multiple sclerosis, brain tumors, post severe brain injury (TBI) and migraine headache. 6. Sensory aphasia. 7. Cognitive impairment with disability to sign a consent form.Patients' Assessment

Data from ClinicalTrials.gov

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