Non-fasting triglyceride levels are thought to play a role in stroke. The investigators hypothesise that the results of a standardised oral triglyceride tolerance test in the subacute setting (3-7 days) after the first ischaemic stroke are associated with the risk of recurrent stroke within 12 months after the index event.
Since high postprandial triglycerides levels may be a risk factor for stroke, we use a combined oral triglyceride and glucose tolerance test in patients who had a first ischemic stroke. Follow-up after one year primarily assesses wether or not a recurrent stroke has occured. The glucose tolerance test is meant to identify patients with metabolic syndrome (and diabetes), since this condition is per se associated with increased levels of triglycerides. Potentially, the post-challenge triglyceride levels only play a role in patients without diabetes or metabolic syndrome. For further details see Ebinger et al. 'The Berlin 'Cream\&Sugar' Study: the prognostic impact of an oral triglyceride tolerance test in patients after acute ischaemic stroke', IJS; 2010,5, 47-51.
Study Type
OBSERVATIONAL
Enrollment
573
see Ebinger et al., IJS, 2010
Charité - Universitätsmedizin Berlin
Berlin, Germany
Recurrent Stroke
The primary end-point of the study is a recurrent fatal or nonfatal stroke within the first 12 months after the event.
Time frame: outcome measure is assessed one year after first ischemic stroke.
MI
Myocardial infarction
Time frame: one year after first ischemic stroke
death
cardiovascular death (death due to any cardiovascular or cerebrovascular event)
Time frame: one year after first ischemic stroke
TIA
transient ischemic attack
Time frame: one year after first ischemic stroke
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