The main objective is to assess the nutritional benefit of probiotics supplementation on premature infants growth. As secondary objectives, different parameters related to probiotics tolerance will be measured.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
SUPPORTIVE_CARE
Masking
QUADRUPLE
Enrollment
199
1 capsule per day, from inclusion to 4 or 6 weeks after inclusion
Service de Nénatologie, Hôpital Femme Mère Enfant
Bron, France
Service de Réanimation Néonatale et Néonatologie, Hôpital de la Croix Rousse
Lyon, France
Service de Réanimation Néonatale, Hôpital Arnaud de Villeneuve
Montpellier, France
Weight (g)
Time frame: From 4 to 6 weeks after inclusion
Growth
measured by: * weight gain (g/day) * height (cm/week) * head circumference(cm/week)
Time frame: between inclusion date and 4 to 6 weeks after inclusion (= end of supplementation period)
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