Comparison of Between ThinSeed™ and OncoSeed™ for Permanent Prostate Brachytherapy

Inclusion Criteria: * Histologically confirmed adenocarcinoma of the prostate, clinical stage T1c - T2b, N0, M0 * Greater than or equal to 40 years of age * Low and Low- Intermediate Risk prostate cancer * Prostate volumes by TRUS ≤ 60 cc * I-PSS score \< 25 (alpha blockers allowed) * Signed study-specific informed consent form prior to study entry Exclusion Criteria: * Lymph node involvement (N1) * Evidence of distant metastases (M1) * Radical surgery for carcinoma of the prostate * Prior pelvic radiation * Major medical or psychiatric illness, which in the investigator's opinion would prevent completion of treatment and would interfere with follow- up or ability to complete questionnaires * Hip prosthesis * Inability or refusal to provide informed consent * Evidence of Previous TURP * Prior hormone therapy * Prior TURP