Study Evaluating Orally Administered AMG 900 in Adult Subjects With Acute Myeloid Leukemia

Inclusion Criteria: * Men or women ≥ 18 years old * Pathologically documented, definitively diagnosed AML that has failed standard treatments or for which no standard therapy is available or the subject refuses standard therapy * Must consent to undergo bone marrow biopsies per schedule of assessments Exclusion Criteria: * White blood cell greater than 20,000 uL * History of or active central nervous system leukemia * Prior allogeneic bone marrow transplant * Subject will not be available for protocol-required study visits or procedures Other Inclusion/ Exclusion Criteria may apply to qualify for enrollment