The benefit of using platelet rich plasma (PRP) in cartilage injuries, and specifically in degenerative ones, has not been assessed yet. Current studies on the PRP healing or repairing effect on knee cartilage degenerative injuries are not conclusive to establish a standard of behavior, although PRP has shown to improve joint functionality and reduce pain. Hypothesis: PRP intra-articular injections in osteoarthritic knees reduces pain and leads to a more effective and lasting functional recovering than corticosteroid intra-articular injections.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
QUADRUPLE
Enrollment
74
a single intra-articular injection
A single betamethasone and bupivacaine intra-articular injection
Hospital Universitario Vall d'Hebron
Barcelona, Barcelona, Spain
The value of the visual analogue scale pain (VAS)
The difference between the baseline and the value of the scale one month after treatment
Time frame: one month after the treatment
the value of pain visual analog scale according to
Time frame: 4 weeks, 3 and 6 months after treatment
the functional level of the knee KOOS
Time frame: 4 weeks, 3 and 6 months after treatment
All reported adverse events
Time frame: 4 weeks, 3 and 6 months after treatment
Scale of the SF36 quality of life
Time frame: 4 weeks, 3 and 6 months after treatment
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