Foveal Cone Outer Segment Resumption to Predict Visual Recovery After Macular Hole Surgery

N/ACompletedNCT01381965

Kyorin University72 enrolled

Overview

Spectral domain optical coherence tomography (SD-OCT) was used to determine whether the repair of photoreceptor cone outer segment tips defect is significantly correlated with the visual outcomes after macular hole surgery.

Spectral domain optical coherence tomography (SD-OCT) was used to calculate the mean length of photoreceptor cone outer segment tips (COST) defect on 1, 3, 6, 9, and 12 months after macular hole surgery. The correlation between the mean length of COST defect and the BCVA was determined. Prognostic factors might have influenced for COST repair was also evaluated by multivariable analysis.

Study Type

INTERVENTIONAL

Allocation

Purpose

TREATMENT

Masking

SINGLE

Enrollment

Conditions

Macular Holes

Interventions

Vitreous surgery for macular holePROCEDURE

Vitreous surgery for macular hole

Eligibility

Sex: ALLMin age: 20 YearsMax age: 90 Years

Medical Language ↔ Plain English

Inclusion Criteria: * macular hole patients with surgically-closed hole Exclusion Criteria: * macular hole patients failed to close hole * presence of retinal diseases including a treated rhegmatogenous retinal detachment, diabetic retinopathy, and high myopia with an axial length \>27.0mm or refractive error \> -8.0 diopters(D). * patients who were not followed at least 6 months

Locations (1)

Makoto Inoue

Mitaka, Tokyo, Japan

Outcomes

Primary Outcomes

Visual acuity

Preoperative, postoperative 1, 3, 6, 9, 12 months

Time frame: one year

Secondary Outcomes

Integrity of cone outer segment tips line

The mean length of cone outer segment tips defect on preoperative and postoperative 1, 3, 6, 9, and 12 months with spectral domain optical coherence tomography

Time frame: one year

Data from ClinicalTrials.gov

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