Long-term Beneficial Metabolic Effects of Adrenalectomy in Subclinical Cushing's Syndrome of Adrenal Incidentaloma

Inclusion Criteria: * patients with both unilateral adrenal incidentaloma and hypercortisolism * definition of hypercortisolism * overnight dexamethasone suppression test, serum cortisol\>1.8ug/dL * 24hr urine cortisol \> upper reference limit Exclusion Criteria: * patients who took medication influencing cortisol secretion * patients with definite clinical feature of cushing syndrome * moon face * abdominal striae * skin or proximal muscle atrophy * metabolic syndrome, hyperthyroidism, hyperparathyroidism, chronic renal failure, rheumatic disease, hematologic disease * patients who took following medication * insulin * oral hypoglycemic agent * thyroid hormone * anti-hyperlipidemic drug * sex hormone * patients who taking steroid hormone or who took steroid hormone more than 2 weeks within 1 year * psychiatric disease